Gene description for FBXO30
Gene name F-box protein 30
Gene symbol FBXO30
Other names/aliases Fbx30
Species Homo sapiens
 Database cross references - FBXO30
ExoCarta ExoCarta_84085
Vesiclepedia VP_84085
Entrez Gene 84085
HGNC 15600
MIM 609101
UniProt Q8TB52  
 FBXO30 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for FBXO30
Molecular Function
    protein binding GO:0005515 IPI
    zinc ion binding GO:0008270 IEA
    ubiquitin protein ligase activity GO:0061630 IEA
Biological Process
    protein ubiquitination GO:0016567 IEA
Subcellular Localization
    cytosol GO:0005829 TAS
 Experiment description of studies that identified FBXO30 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for FBXO30
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CUL1 8454
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 SCIN 85477
Affinity Capture-MS Homo sapiens
3 DNALI1  
Affinity Capture-MS Homo sapiens
4 Skp1a 21402
Affinity Capture-MS Mus musculus
5 C16orf70  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 PEX19 5824
Affinity Capture-MS Homo sapiens
7 DQX1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 ACTA2 59
Affinity Capture-MS Homo sapiens
9 APC  
Two-hybrid Homo sapiens
10 SKP1 6500
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
11 CUL3 8452
Affinity Capture-MS Homo sapiens
12 RBX1 9978
Affinity Capture-MS Homo sapiens
13 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
14 CALM1 801
Affinity Capture-MS Homo sapiens
15 CTAG2  
Affinity Capture-MS Homo sapiens
16 MAP3K7  
Affinity Capture-MS Homo sapiens
17 SETDB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 FBXO34  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 MYO1C 4641
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 NXF1 10482
Affinity Capture-RNA Homo sapiens
21 TNNC1  
Affinity Capture-MS Homo sapiens
22 QSOX2 169714
Affinity Capture-MS Homo sapiens
23 MOV10 4343
Affinity Capture-RNA Homo sapiens
24 MYO6 4646
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 AURKA 6790
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 BCL7C  
Affinity Capture-MS Homo sapiens
27 ACTB 60
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 FLII 2314
Affinity Capture-MS Homo sapiens
29 Dynll1 56455
Affinity Capture-MS Mus musculus
30 Trappc11  
Affinity Capture-MS Mus musculus
31 DYNLL2 140735
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 PSME1 5720
Affinity Capture-MS Homo sapiens
33 ACTC1 70
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
34 RPA3 6119
Proximity Label-MS Homo sapiens
35 ACTG1 71
Affinity Capture-MS Homo sapiens
36 DYNLL1 8655
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 MYO1B 4430
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 PNKD  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 CASQ2 845
Affinity Capture-MS Homo sapiens
40 HIF1A 3091
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml



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