Gene description for SDF2
Gene name stromal cell-derived factor 2
Gene symbol SDF2
Other names/aliases -
Species Homo sapiens
 Database cross references - SDF2
ExoCarta ExoCarta_6388
Vesiclepedia VP_6388
Entrez Gene 6388
HGNC 10675
MIM 602934
UniProt Q99470  
 SDF2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for SDF2
Molecular Function
    misfolded protein binding GO:0051787 IMP
Biological Process
    chaperone cofactor-dependent protein refolding GO:0051085 IMP
Subcellular Localization
    endoplasmic reticulum GO:0005783 IDA
    protein folding chaperone complex GO:0101031 IPI
 Experiment description of studies that identified SDF2 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for SDF2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TOMM40 10452
Co-fractionation Homo sapiens
2 HNRNPD 3184
Two-hybrid Homo sapiens
3 HSPA5 3309
Affinity Capture-MS Homo sapiens
4 MYCN  
Affinity Capture-MS Homo sapiens
5 HSPB2  
Two-hybrid Homo sapiens
6 PSG1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 Tpm1 22003
Affinity Capture-MS Mus musculus
8 C11orf54 28970
Co-fractionation Homo sapiens
9 ALS2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 CALR3  
Proximity Label-MS Homo sapiens
11 RNF128  
Affinity Capture-MS Homo sapiens
12 CNTNAP1 8506
Affinity Capture-MS Homo sapiens
13 TUBB8 347688
Affinity Capture-MS Homo sapiens
14 NUBPL 80224
Affinity Capture-MS Homo sapiens
15 PLD4  
Affinity Capture-MS Homo sapiens
16 UBC 7316
Reconstituted Complex Homo sapiens
17 EGFR 1956
Affinity Capture-MS Homo sapiens
18 TUBA1A 7846
Affinity Capture-MS Homo sapiens
19 MYC  
Affinity Capture-MS Homo sapiens
20 SDF2L1 23753
Affinity Capture-MS Homo sapiens
21 SYNJ2BP 55333
Co-fractionation Homo sapiens
22 ZNRF4  
Affinity Capture-MS Homo sapiens
23 DMWD  
Affinity Capture-MS Homo sapiens
24 ZER1 10444
Affinity Capture-MS Homo sapiens
25 VDAC3 7419
Co-fractionation Homo sapiens
26 BMP1 649
Affinity Capture-MS Homo sapiens
27 Sept9  
Affinity Capture-MS Mus musculus
28 PTPRO 5800
Affinity Capture-MS Homo sapiens
29 PVRL3 25945
Affinity Capture-MS Homo sapiens
30 TOMM5  
Co-fractionation Homo sapiens
31 DNAJB11 51726
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 PTK7 5754
Cross-Linking-MS (XL-MS) Homo sapiens
View the network image/svg+xml
 Pathways in which SDF2 is involved
No pathways found





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