Gene description for LYPD6B
Gene name LY6/PLAUR domain containing 6B
Gene symbol LYPD6B
Other names/aliases CT116
LYPD7
Species Homo sapiens
 Database cross references - LYPD6B
ExoCarta ExoCarta_130576
Entrez Gene 130576
HGNC 27018
UniProt Q8NI32  
 LYPD6B identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for LYPD6B
Subcellular Localization
    plasma membrane GO:0005886 IEA
    anchored component of membrane GO:0031225 IEA
 Experiment description of studies that identified LYPD6B in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for LYPD6B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LYPD6B is involved
No pathways found





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