|
 Gene description for CAB39L |
| Gene name |
calcium binding protein 39-like |
| Gene symbol |
CAB39L |
| Other names/aliases |
MO25-BETA
MO2L
bA103J18.3 |
| Species |
Homo sapiens |
| Database cross references - CAB39L |
| ExoCarta |
ExoCarta_81617 |
| Entrez Gene |
81617 |
| HGNC |
20290 |
| MIM |
612175 |
| UniProt |
Q9H9S4
|
| CAB39L identified in exosomes derived from the following tissue/cell type |
|
Squamous carcinoma cells
|
20124223
|
|
Urine
|
19056867
|
|
Urine
|
22418980
|
|
Urine
|
22418980
|
| Gene ontology annotations for CAB39L |
|
|
| Experiment description of studies that identified CAB39L in exosomes |
| 1 |
| Experiment ID |
191 |
| ISEV standards |
|
✘
|
EV Biophysical techniques |
|
✔
Alix
|
EV Cytosolic markers |
|
✔
CD81|CD9
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
20124223
|
| Organism |
Homo sapiens |
| Experiment description |
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. |
| Authors |
Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK. |
| Journal name |
Mol Cell Proteomics
|
| Publication year |
2010 |
| Sample |
Squamous carcinoma cells |
| Sample name |
Squamous carcinoma cell (A431) |
| Isolation/purification methods |
Differential centrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| 2 |
| Experiment ID |
63 |
| ISEV standards |
|
✘
|
EV Biophysical techniques |
|
✘
|
EV Cytosolic markers |
|
✔
AQP2
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
19056867
|
| Organism |
Homo sapiens |
| Experiment description |
Large-scale proteomics and phosphoproteomics of urinary exosomes. |
| Authors |
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA |
| Journal name |
JASN
|
| Publication year |
2009 |
| Sample |
Urine |
| Sample name |
Urine - Normal |
| Isolation/purification methods |
Differential centrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry [LTQ]
Western blotting |
|
|
| 3 |
| Experiment ID |
196 |
| ISEV standards |
|
✔
EM
|
EV Biophysical techniques |
|
✔
Alix|TSG101|HSP70
|
EV Cytosolic markers |
|
✔
CD9
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
22418980
|
| Organism |
Homo sapiens |
| Experiment description |
A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. |
| Authors |
Raj DA, Fiume I, Capasso G, Pocsfalvi G. |
| Journal name |
Kidney Int
|
| Publication year |
2012 |
| Sample |
Urine |
| Sample name |
Urine - Normal high density |
| Isolation/purification methods |
Differential centrifugation
Sucrose cushion |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| 4 |
| Experiment ID |
197 |
| ISEV standards |
|
✔
EM
|
EV Biophysical techniques |
|
✔
Alix|TSG101|HSP70
|
EV Cytosolic markers |
|
✔
CD9
|
EV Membrane markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
22418980
|
| Organism |
Homo sapiens |
| Experiment description |
A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. |
| Authors |
Raj DA, Fiume I, Capasso G, Pocsfalvi G. |
| Journal name |
Kidney Int
|
| Publication year |
2012 |
| Sample |
Urine |
| Sample name |
Urine - Normal low density |
| Isolation/purification methods |
Differential centrifugation
Sucrose cushion |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| Protein-protein interactions for CAB39L |
|
|
| Pathways in which CAB39L is involved |
|
|
|
