Gene description for GBP1
Gene name	guanylate binding protein 1, interferon-inducible
Gene symbol	GBP1
Other names/aliases	-
Species	Homo sapiens
Database cross references - GBP1
ExoCarta	ExoCarta_2633
Entrez Gene	2633
HGNC	4182
MIM	600411
UniProt	P32455
GBP1 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for GBP1

Molecular Function     actin binding GO:0003779 IDA     GTP binding GO:0005525 IEA     identical protein binding GO:0042802 IPI     GTPase activity GO:0003924 IEA     protein binding GO:0005515 IPI     enzyme binding GO:0019899 IPI     spectrin binding GO:0030507 IPI     Hsp90 protein binding GO:0051879 IPI     cytokine binding GO:0019955 IPI Biological Process     negative regulation of interleukin-2 secretion GO:1900041 IMP     cytokine-mediated signaling pathway GO:0019221 TAS     negative regulation of substrate adhesion-dependent cell spreading GO:1900025 IMP     negative regulation of T cell receptor signaling pathway GO:0050860 IMP     negative regulation of protein localization to plasma membrane GO:1903077 IMP     regulation of protein localization to plasma membrane GO:1903076 IGI     defense response to virus GO:0051607 IEA     regulation of calcium-mediated signaling GO:0050848 IMP     metabolic process GO:0008152 IEA     interferon-gamma-mediated signaling pathway GO:0060333 TAS     negative regulation of ERK1 and ERK2 cascade GO:0070373 IMP Subcellular Localization     cytosol GO:0005829 TAS     Golgi membrane GO:0000139 IEA     extracellular region GO:0005576 IEA