Gene description for ZNF317
Gene name zinc finger protein 317
Gene symbol ZNF317
Other names/aliases -
Species Homo sapiens
 Database cross references - ZNF317
ExoCarta ExoCarta_57693
Vesiclepedia VP_57693
Entrez Gene 57693
HGNC 13507
MIM 613864
UniProt Q96PQ6  
 ZNF317 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for ZNF317
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
Subcellular Localization
    nucleus GO:0005634 HDA
    nucleus GO:0005634 IBA
 Experiment description of studies that identified ZNF317 in exosomes
1
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for ZNF317
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 WDR46  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 RPL13 6137
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 ZNF668  
Affinity Capture-MS Homo sapiens
4 RPL23A 6147
Affinity Capture-MS Homo sapiens
5 H1FNT  
Affinity Capture-MS Homo sapiens
6 OASL 8638
Affinity Capture-MS Homo sapiens
7 RBMY1F  
Two-hybrid Homo sapiens
8 C11orf57  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
9 RPS3A 6189
Affinity Capture-MS Homo sapiens
10 RPS2 6187
Affinity Capture-MS Homo sapiens
11 GBP1 2633
Affinity Capture-MS Homo sapiens
12 RBMY1A1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
13 NOTCH2 4853
Affinity Capture-MS Homo sapiens
14 MRPL30  
Affinity Capture-MS Homo sapiens
15 BAHD1  
Two-hybrid Homo sapiens
16 TUBA8 51807
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 HECTD3 79654
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 HIST1H1D 3007
Affinity Capture-MS Homo sapiens
19 ZNF648  
Two-hybrid Homo sapiens
20 CLK2 1196
Two-hybrid Homo sapiens
21 CPNE2 221184
Affinity Capture-MS Homo sapiens
22 NOP2 4839
Affinity Capture-MS Homo sapiens
23 CUL3 8452
Affinity Capture-MS Homo sapiens
24 ZNF48  
Affinity Capture-MS Homo sapiens
25 RPL3 6122
Affinity Capture-MS Homo sapiens
26 RPL26 6154
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 PNMAL1  
Affinity Capture-MS Homo sapiens
28 RPL4 6124
Affinity Capture-MS Homo sapiens
29 ZBTB47  
Affinity Capture-MS Homo sapiens
30 ASXL1  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
31 RPL26L1 51121
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 ZBTB48  
Two-hybrid Homo sapiens
33 RBM4 5936
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 RSBN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 AEN  
Two-hybrid Homo sapiens
36 TRIM28 10155
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 RPL7A 6130
Affinity Capture-MS Homo sapiens
38 ZNF408  
Two-hybrid Homo sapiens
39 LLPH  
Affinity Capture-MS Homo sapiens
40 NPW  
Affinity Capture-MS Homo sapiens
41 GLI4  
Affinity Capture-MS Homo sapiens
42 RPL23AP32 56969
Affinity Capture-MS Homo sapiens
43 ZNF524  
Two-hybrid Homo sapiens
44 CCDC137  
Affinity Capture-MS Homo sapiens
45 RPL28 6158
Affinity Capture-MS Homo sapiens
46 RPL36 25873
Affinity Capture-MS Homo sapiens
47 CIB3  
Two-hybrid Homo sapiens
48 KRT40  
Two-hybrid Homo sapiens
49 SCRIB 23513
Affinity Capture-MS Homo sapiens
50 PPAN 56342
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 RPLP0 6175
Affinity Capture-MS Homo sapiens
52 CCDC140  
Affinity Capture-MS Homo sapiens
53 MAGEB2 4113
Affinity Capture-MS Homo sapiens
54 SRP14 6727
Affinity Capture-MS Homo sapiens
55 ZNF467  
Affinity Capture-MS Homo sapiens
56 MRPS18A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 GNL3 26354
Affinity Capture-MS Homo sapiens
58 RBM10  
Two-hybrid Homo sapiens
59 RBMY1J  
Two-hybrid Homo sapiens
60 KRTAP10-9  
Two-hybrid Homo sapiens
View the network image/svg+xml



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