Gene description for POU2F2
Gene name POU class 2 homeobox 2
Gene symbol POU2F2
Other names/aliases OCT2
Species Homo sapiens
 Database cross references - POU2F2
ExoCarta ExoCarta_5452
Entrez Gene 5452
HGNC 9213
MIM 164176
UniProt P09086  
 POU2F2 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for POU2F2
Molecular Function
    protein domain specific binding GO:0019904 IEA
    sequence-specific DNA binding transcription factor activity GO:0003700 IEA
    sequence-specific DNA binding GO:0043565 IDA
Biological Process
    transcription from RNA polymerase II promoter GO:0006366 TAS
    humoral immune response GO:0006959 TAS
    immunoglobulin secretion involved in immune response GO:0002380 IEA
    positive regulation of transcription, DNA-templated GO:0045893 IEA
    mature B cell differentiation GO:0002335 IEA
    cell maturation GO:0048469 IEA
Subcellular Localization
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified POU2F2 in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for POU2F2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 AR 367
Reconstituted Complex Homo sapiens
2 XRCC6 2547
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
3 ESR1  
Reconstituted Complex Homo sapiens
4 TBP  
Invivo Homo sapiens
Invitro Homo sapiens
5 POU2F2 5452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 NR3C1 2908
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Invitro Homo sapiens
Reconstituted Complex Homo sapiens
7 GAPDH 2597
Reconstituted Complex Homo sapiens
8 MNAT1  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
9 PGR  
Reconstituted Complex Homo sapiens
10 HMGB2 3148
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Far Western Homo sapiens
View the network image/svg+xml
 Pathways in which POU2F2 is involved
No pathways found

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