Gene description for GPR179
Gene name G protein-coupled receptor 179
Gene symbol GPR179
Other names/aliases CSNB1E
GPR158L
GPR158L1
Species Homo sapiens
 Database cross references - GPR179
ExoCarta ExoCarta_440435
Vesiclepedia VP_440435
Entrez Gene 440435
HGNC 31371
MIM 614515
UniProt Q6PRD1  
 GPR179 identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for GPR179
Molecular Function
    G protein-coupled receptor activity GO:0004930 IEA
    protein binding GO:0005515 IPI
Biological Process
    G protein-coupled receptor signaling pathway GO:0007186 IEA
    visual perception GO:0007601 IMP
Subcellular Localization
    dendrite GO:0030425 IDA
    postsynaptic membrane GO:0045211 ISS
 Experiment description of studies that identified GPR179 in sEVs
1
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for GPR179
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 BRCA2 675
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which GPR179 is involved
No pathways found





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