Gene description for COL11A1
Gene name collagen, type XI, alpha 1
Gene symbol COL11A1
Other names/aliases CO11A1
COLL6
STL2
Species Homo sapiens
 Database cross references - COL11A1
ExoCarta ExoCarta_1301
Entrez Gene 1301
HGNC 2186
MIM 120280
UniProt P12107  
 COL11A1 identified in exosomes derived from the following tissue/cell type
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for COL11A1
Molecular Function
    protein binding, bridging GO:0030674 NAS
    extracellular matrix binding GO:0050840 NAS
    extracellular matrix structural constituent GO:0005201 NAS
    metal ion binding GO:0046872 IEA
Biological Process
    embryonic skeletal system morphogenesis GO:0048704 IEA
    chondrocyte development GO:0002063 IEA
    collagen catabolic process GO:0030574 TAS
    sensory perception of sound GO:0007605 IMP
    cartilage condensation GO:0001502 IEA
    endodermal cell differentiation GO:0035987 IEP
    ossification GO:0001503 IEA
    proteoglycan metabolic process GO:0006029 IEA
    inner ear morphogenesis GO:0042472 IEA
    visual perception GO:0007601 IMP
    tendon development GO:0035989 IEA
    extracellular matrix organization GO:0030198 TAS
    ventricular cardiac muscle tissue morphogenesis GO:0055010 IEA
    detection of mechanical stimulus involved in sensory perception of sound GO:0050910 IMP
    extracellular matrix disassembly GO:0022617 TAS
    collagen fibril organization GO:0030199 NAS
Subcellular Localization
    extracellular region GO:0005576 TAS
    endoplasmic reticulum lumen GO:0005788 TAS
    collagen type XI trimer GO:0005592 NAS
 Experiment description of studies that identified COL11A1 in exosomes
1
Experiment ID 193
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63|CD9
EV Membrane markers
PHB
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC.
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 194
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC.
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 195
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC.
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for COL11A1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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