Gene description for AP5Z1
Gene name adaptor-related protein complex 5, zeta 1 subunit
Gene symbol AP5Z1
Other names/aliases KIAA0415
SPG48
zeta
Species Homo sapiens
 Database cross references - AP5Z1
ExoCarta ExoCarta_9907
Entrez Gene 9907
HGNC 22197
MIM 613653
UniProt O43299  
 AP5Z1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for AP5Z1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    endosomal transport GO:0016197 IMP
    protein transport GO:0015031 IEA
    double-strand break repair via homologous recombination GO:0000724 IMP
Subcellular Localization
    cytoplasm GO:0005737 IDA
    AP-5 adaptor complex GO:0044599 IEA
    nucleoplasm GO:0005654 IDA
    nucleus GO:0005634 IDA
    AP-type membrane coat adaptor complex GO:0030119 NAS
 Experiment description of studies that identified AP5Z1 in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for AP5Z1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which AP5Z1 is involved
No pathways found





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