Gene description for FGF18
Gene name	fibroblast growth factor 18
Gene symbol	FGF18
Other names/aliases	FGF-18 ZFGF5
Species	Homo sapiens
Database cross references - FGF18
ExoCarta	ExoCarta_8817
Vesiclepedia	VP_8817
Entrez Gene	8817
HGNC	3674
MIM	603726
UniProt	O76093
FGF18 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for FGF18

Molecular Function     type 1 fibroblast growth factor receptor binding GO:0005105 IBA     type 1 fibroblast growth factor receptor binding GO:0005105 IDA     type 2 fibroblast growth factor receptor binding GO:0005111 IBA     type 2 fibroblast growth factor receptor binding GO:0005111 IDA     growth factor activity GO:0008083 IBA Biological Process     angiogenesis GO:0001525 IEA     regulation of endothelial cell proliferation GO:0001936 IDA     intramembranous ossification GO:0001957 IEA     endochondral ossification GO:0001958 IEA     chondrocyte development GO:0002063 IEA     signal transduction GO:0007165 TAS     cell-cell signaling GO:0007267 TAS     cell population proliferation GO:0008283 IEA     positive regulation of cell population proliferation GO:0008284 IBA     fibroblast growth factor receptor signaling pathway GO:0008543 IBA     anatomical structure morphogenesis GO:0009653 TAS     neurogenesis GO:0022008 IBA     lung development GO:0030324 IEA     regulation of cell migration GO:0030334 IBA     positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 IEA     positive regulation of chondrocyte differentiation GO:0032332 IEA     positive regulation of MAP kinase activity GO:0043406 IDA     positive regulation of MAPK cascade GO:0043410 IBA     positive regulation of blood vessel endothelial cell migration GO:0043536 IGI     positive regulation of angiogenesis GO:0045766 IGI     vascular endothelial growth factor receptor signaling pathway GO:0048010 IEA     ERK1 and ERK2 cascade GO:0070371 IEA     positive regulation of ERK1 and ERK2 cascade GO:0070374 IEA     regulation of sprouting angiogenesis GO:1903670 IDA     positive regulation of endothelial cell chemotaxis to fibroblast growth factor GO:2000546 IDA Subcellular Localization     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IBA     nucleolus GO:0005730 IDA     cytoplasm GO:0005737 IBA