Gene description for PLEKHG4B
Gene name pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
Gene symbol PLEKHG4B
Other names/aliases -
Species Homo sapiens
 Database cross references - PLEKHG4B
ExoCarta ExoCarta_153478
Entrez Gene 153478
HGNC 29399
UniProt Q96PX9  
 PLEKHG4B identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for PLEKHG4B
Molecular Function
    Rho guanyl-nucleotide exchange factor activity GO:0005089 IEA
Biological Process
    positive regulation of GTPase activity GO:0043547 IEA
 Experiment description of studies that identified PLEKHG4B in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PLEKHG4B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PLEKHG4B is involved
No pathways found





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