Gene description for ARHGEF11
Gene name	Rho guanine nucleotide exchange factor (GEF) 11
Gene symbol	ARHGEF11
Other names/aliases	GTRAP48 PDZ-RHOGEF
Species	Homo sapiens
Database cross references - ARHGEF11
ExoCarta	ExoCarta_9826
Entrez Gene	9826
HGNC	14580
MIM	605708
UniProt	O15085
ARHGEF11 identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for ARHGEF11

Molecular Function     protein binding GO:0005515 IPI     G-protein coupled receptor binding GO:0001664 IDA     Rho guanyl-nucleotide exchange factor activity GO:0005089 TAS     GTPase activator activity GO:0005096 IEA Biological Process     cytokinesis GO:0000910 NAS     positive regulation of apoptotic process GO:0043065 TAS     regulation of cell growth GO:0001558 NAS     axon guidance GO:0007411 TAS     regulation of small GTPase mediated signal transduction GO:0051056 TAS     establishment of cell polarity GO:0030010 NAS     movement of cell or subcellular component GO:0006928 NAS     positive regulation of transcription, DNA-templated GO:0045893 IDA     small GTPase mediated signal transduction GO:0007264 TAS     termination of G-protein coupled receptor signaling pathway GO:0038032 IEA     positive regulation of GTPase activity GO:0043547 TAS     striated muscle contraction GO:0006941 NAS     actin cytoskeleton organization GO:0030036 NAS     G-protein coupled receptor signaling pathway GO:0007186 TAS     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     Rho protein signal transduction GO:0007266 IDA     apoptotic signaling pathway GO:0097190 TAS Subcellular Localization     cytosol GO:0005829 TAS     intracellular GO:0005622 IC     membrane GO:0016020 IEA     cytoplasm GO:0005737 IDA