Gene description for DUS1L
Gene name dihydrouridine synthase 1-like (S. cerevisiae)
Gene symbol DUS1L
Other names/aliases DUS1
PP3111
Species Homo sapiens
 Database cross references - DUS1L
ExoCarta ExoCarta_64118
Entrez Gene 64118
HGNC 30086
UniProt Q6P1R4  
 DUS1L identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for DUS1L
Molecular Function
    flavin adenine dinucleotide binding GO:0050660 IEA
    tRNA dihydrouridine synthase activity GO:0017150 IEA
Biological Process
    oxidation-reduction process GO:0055114 IEA
    tRNA dihydrouridine synthesis GO:0002943 IEA
 Experiment description of studies that identified DUS1L in exosomes
1
Experiment ID 236
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for DUS1L
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which DUS1L is involved
No pathways found





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