Gene description for EDNRB
Gene name	endothelin receptor type B
Gene symbol	EDNRB
Other names/aliases	ABCDS ET-B ET-BR ETB ETBR ETRB HSCR HSCR2 WS4A
Species	Homo sapiens
Database cross references - EDNRB
ExoCarta	ExoCarta_1910
Vesiclepedia	VP_1910
Entrez Gene	1910
HGNC	3180
MIM	131244
UniProt	P24530
EDNRB identified in exosomes derived from the following tissue/cell type
Melanoma cells	25950383
Melanoma cells	25950383

Gene ontology annotations for EDNRB

Molecular Function     protein binding GO:0005515 IPI     peptide hormone binding GO:0017046 IPI     type 1 angiotensin receptor binding GO:0031702 IEA     endothelin receptor activity GO:0004962 IMP Biological Process     positive regulation of penile erection GO:0060406 IEA     regulation of fever generation GO:0031620 IEA     cellular response to lipopolysaccharide GO:0071222 IEA     positive regulation of protein phosphorylation GO:0001934 IEA     enteric nervous system development GO:0048484 ISS     positive regulation of cytosolic calcium ion concentration GO:0007204 IEA     negative regulation of transcription from RNA polymerase II promoter GO:0000122 ISS     positive regulation of renal sodium excretion GO:0035815 IEA     neural crest cell migration GO:0001755 IEA     regulation of blood pressure GO:0008217 IEA     negative regulation of adenylate cyclase activity GO:0007194 TAS     sensory perception of pain GO:0019233 IEA     regulation of epithelial cell proliferation GO:0050678 IEA     endothelin receptor signaling pathway GO:0086100 IMP     positive regulation of cell proliferation GO:0008284 IEA     phospholipase C-activating G-protein coupled receptor signaling pathway GO:0007200 IEA     vasodilation GO:0042311 IEA     peripheral nervous system development GO:0007422 IEA     epithelial fluid transport GO:0042045 IEA     negative regulation of neuron maturation GO:0014043 ISS     response to organic cyclic compound GO:0014070 IEA     posterior midgut development GO:0007497 IEA     response to pain GO:0048265 IEA     regulation of sensory perception of pain GO:0051930 IEA     negative regulation of apoptotic process GO:0043066 IEA     vasoconstriction GO:0042310 IMP     nervous system development GO:0007399 TAS     enteric smooth muscle cell differentiation GO:0035645 ISS     regulation of pH GO:0006885 IEA     cGMP-mediated signaling GO:0019934 IEA     vein smooth muscle contraction GO:0014826 IMP     aging GO:0007568 IEA     positive regulation of urine volume GO:0035810 IEA     melanocyte differentiation GO:0030318 IEA     cell surface receptor signaling pathway GO:0007166 TAS     macrophage chemotaxis GO:0048246 IMP     negative regulation of cellular protein metabolic process GO:0032269 IMP Subcellular Localization     cytosol GO:0005829 IEA     integral component of plasma membrane GO:0005887 TAS     plasma membrane GO:0005886 TAS     nuclear membrane GO:0031965 IEA     membrane raft GO:0045121 IEA