Gene description for IGLC6
Gene name immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene)
Gene symbol IGLC6
Other names/aliases IGLC
Species Homo sapiens
 Database cross references - IGLC6
ExoCarta ExoCarta_3542
Vesiclepedia VP_3542
Entrez Gene 3542
HGNC 5860
 IGLC6 identified in exosomes derived from the following tissue/cell type
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
 Gene ontology annotations for IGLC6
Molecular Function
    antigen binding GO:0003823 IBA
Biological Process
    adaptive immune response GO:0002250 NAS
    immunoglobulin mediated immune response GO:0016064 IBA
    B cell receptor signaling pathway GO:0050853 NAS
Subcellular Localization
    extracellular region GO:0005576 TAS
    extracellular space GO:0005615 HDA
    extracellular space GO:0005615 NAS
    plasma membrane GO:0005886 NAS
    plasma membrane GO:0005886 TAS
    IgG immunoglobulin complex GO:0071735 IBA
    IgG immunoglobulin complex GO:0071735 NAS
    IgD immunoglobulin complex GO:0071738 NAS
    IgE immunoglobulin complex GO:0071742 NAS
    IgA immunoglobulin complex GO:0071745 NAS
    IgM immunoglobulin complex GO:0071753 NAS
 Experiment description of studies that identified IGLC6 in exosomes
1
Experiment ID 231
MISEV standards
Biophysical techniques
Alix|CD63|CD9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 232
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 233
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for IGLC6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 IGLL5 100423062
Affinity Capture-MS Homo sapiens
2 OR2A4 79541
Affinity Capture-MS Homo sapiens
3 HCN1  
Affinity Capture-MS Homo sapiens
4 PSMA4 5685
Affinity Capture-MS Homo sapiens
5 C18orf21  
Affinity Capture-MS Homo sapiens
6 ST6GALNAC6 30815
Affinity Capture-MS Homo sapiens
7 PTDSS1 9791
Affinity Capture-MS Homo sapiens
8 PIGT 51604
Affinity Capture-MS Homo sapiens
9 UBE2U  
Affinity Capture-MS Homo sapiens
10 FOXN3 1112
Affinity Capture-MS Homo sapiens
11 PHF11 51131
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which IGLC6 is involved
No pathways found





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