Gene description for PRSS16
Gene name protease, serine, 16 (thymus)
Gene symbol PRSS16
Other names/aliases TSSP
Species Homo sapiens
 Database cross references - PRSS16
ExoCarta ExoCarta_10279
Vesiclepedia VP_10279
Entrez Gene 10279
HGNC 9480
MIM 607169
UniProt Q9NQE7  
 PRSS16 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for PRSS16
Molecular Function
    serine-type peptidase activity GO:0008236 NAS
    dipeptidyl-peptidase activity GO:0008239 IBA
    serine-type exopeptidase activity GO:0070008 IEA
Biological Process
    proteolysis GO:0006508 IEA
    protein catabolic process GO:0030163 NAS
Subcellular Localization
    lysosome GO:0005764 IBA
    lysosome GO:0005764 IDA
    endosome GO:0005768 IBA
    endosome GO:0005768 IDA
 Experiment description of studies that identified PRSS16 in exosomes
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PRSS16
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CAPNS2 84290
Affinity Capture-MS Homo sapiens
2 CASP14 23581
Affinity Capture-MS Homo sapiens
3 SERPINB3 6317
Affinity Capture-MS Homo sapiens
4 SERPINA12  
Affinity Capture-MS Homo sapiens
5 IL37  
Affinity Capture-MS Homo sapiens
6 KLK5 25818
Affinity Capture-MS Homo sapiens
7 RNASE7 84659
Affinity Capture-MS Homo sapiens
8 SERPINB4 6318
Affinity Capture-MS Homo sapiens
9 POF1B 79983
Affinity Capture-MS Homo sapiens
10 CDSN 1041
Affinity Capture-MS Homo sapiens
11 DSG1 1828
Affinity Capture-MS Homo sapiens
12 S100A7 6278
Affinity Capture-MS Homo sapiens
13 PLBD1 79887
Affinity Capture-MS Homo sapiens
14 SERPINA3 12
Affinity Capture-MS Homo sapiens
15 CST6  
Affinity Capture-MS Homo sapiens
16 SBSN 374897
Affinity Capture-MS Homo sapiens
17 AZGP1 563
Affinity Capture-MS Homo sapiens
18 ALOX12B  
Affinity Capture-MS Homo sapiens
19 NEFH 4744
Affinity Capture-MS Homo sapiens
20 HAL 3034
Affinity Capture-MS Homo sapiens
21 ACADSB 36
Co-fractionation Homo sapiens
22 GSDMA 284110
Affinity Capture-MS Homo sapiens
23 TGM3 7053
Affinity Capture-MS Homo sapiens
24 KLK10 5655
Affinity Capture-MS Homo sapiens
25 GM2A 2760
Affinity Capture-MS Homo sapiens
26 KLK7 5650
Affinity Capture-MS Homo sapiens
27 MCM2 4171
Affinity Capture-MS Homo sapiens
28 TGM5  
Affinity Capture-MS Homo sapiens
29 CHRM5  
Two-hybrid Homo sapiens
30 SERPINB8 5271
Affinity Capture-MS Homo sapiens
31 CBWD3  
Affinity Capture-MS Homo sapiens
32 DHRS4 10901
Affinity Capture-MS Homo sapiens
33 CPA4 51200
Affinity Capture-MS Homo sapiens
34 ACPP 55
Affinity Capture-MS Homo sapiens
35 TGM1 7051
Affinity Capture-MS Homo sapiens
36 SERPINB7 8710
Affinity Capture-MS Homo sapiens
37 SDR9C7  
Affinity Capture-MS Homo sapiens
38 SOGA3  
Affinity Capture-MS Homo sapiens
39 FLG 2312
Affinity Capture-MS Homo sapiens
40 CTSH 1512
Affinity Capture-MS Homo sapiens
41 KPRP 448834
Affinity Capture-MS Homo sapiens
42 FLG2 388698
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PRSS16 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here