Gene description for LRP1B
Gene name low density lipoprotein receptor-related protein 1B
Gene symbol LRP1B
Other names/aliases LRP-DIT
LRPDIT
Species Homo sapiens
 Database cross references - LRP1B
ExoCarta ExoCarta_53353
Entrez Gene 53353
HGNC 6693
MIM 608766
UniProt Q9NZR2  
 LRP1B identified in exosomes derived from the following tissue/cell type
Plasma 19028452    
 Gene ontology annotations for LRP1B
Molecular Function
    low-density lipoprotein receptor activity GO:0005041 IEA
    calcium ion binding GO:0005509 IEA
Biological Process
    receptor-mediated endocytosis GO:0006898 IEA
    protein transport GO:0015031 TAS
Subcellular Localization
    receptor complex GO:0043235 IDA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified LRP1B in exosomes
1
Experiment ID 44
ISEV standards
IEM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19028452    
Organism Homo sapiens
Experiment description Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein.
Authors Looze C, Yui D, Leung L, Ingham M, Kaler M, Yao X, Wu WW, Shen RF, Daniels MP, Levine SJ
Journal name BBRC
Publication year 2009
Sample Plasma
Sample name Plasma
Isolation/purification methods Filtration
Size exclusion
Sucrose density gradient
Flotation density 1.15-1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for LRP1B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LRP1B is involved
No pathways found





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