Gene ontology annotations for DFNA5
Experiment description of studies that identified DFNA5 in exosomes
1
Experiment ID
488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Homo sapiens
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Mesenchymal stem cells
Sample name
UCMSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
2
Experiment ID
211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
4
Experiment ID
834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
5
Experiment ID
835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for DFNA5
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
ZSCAN29
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
2
GYPA
Affinity Capture-MS
Homo sapiens
3
PTN
Two-hybrid
Homo sapiens
4
CEP63
Affinity Capture-MS
Homo sapiens
5
MUL1
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
6
TIFA
Two-hybrid
Homo sapiens
7
PLEC
5339
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
8
SIGLECL1
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
9
KIF14
9928
Affinity Capture-MS
Homo sapiens
10
BTNL9
Affinity Capture-MS
Homo sapiens
11
KLC3
Affinity Capture-MS
Homo sapiens
12
CD70
970
Affinity Capture-MS
Homo sapiens
13
EFNB1
1947
Affinity Capture-MS
Homo sapiens
14
C19orf38
Affinity Capture-MS
Homo sapiens
15
EGFR
1956
Affinity Capture-MS
Homo sapiens
16
OCIAD1
54940
Affinity Capture-MS
Homo sapiens
17
RPS3
6188
Affinity Capture-MS
Homo sapiens
18
MRS2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
19
APEX1
328
Affinity Capture-RNA
Homo sapiens
20
BIRC6
57448
Affinity Capture-MS
Homo sapiens
21
COMTD1
118881
Affinity Capture-MS
Homo sapiens
22
C16orf58
64755
Affinity Capture-MS
Homo sapiens
23
NTRK1
4914
Affinity Capture-MS
Homo sapiens
24
GPR45
Affinity Capture-MS
Homo sapiens
25
HVCN1
84329
Affinity Capture-MS
Homo sapiens
26
FAM174A
345757
Affinity Capture-MS
Homo sapiens
27
AGPAT6
137964
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
28
TPST2
8459
Affinity Capture-MS
Homo sapiens
29
SCN2B
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
30
SNW1
22938
Affinity Capture-MS
Homo sapiens
31
SLC27A2
11001
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
32
UQCRH
7388
Affinity Capture-MS
Homo sapiens
33
EPHA1
2041
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
34
B3GNT8
Affinity Capture-MS
Homo sapiens
35
TACSTD2
4070
Affinity Capture-MS
Homo sapiens
36
CDC5L
988
Affinity Capture-MS
Homo sapiens
View the network
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Pathways in which DFNA5 is involved