Experiment description of studies that identified ERC2 in sEVs

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for ERC2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 LSP1 4046 Affinity Capture-Western Homo sapiens 2 Cd2ap 12488 Affinity Capture-MS Mus musculus 3 BSN   Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 4 RIMS1   Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Co-fractionation Homo sapiens 5 PPFIA2 8499 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 6 IQCB1   Affinity Capture-MS Homo sapiens 7 HIST1H2BC 8347 Cross-Linking-MS (XL-MS) Homo sapiens 8 PPFIA1 8500 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 9 UBE3A 7337 Affinity Capture-MS Homo sapiens 10 ERGIC2 51290 Proximity Label-MS Homo sapiens 11 UNC13A 23025 Affinity Capture-Western Homo sapiens 12 GIT1 28964 Affinity Capture-Western Homo sapiens 13 KRT38 8687 Affinity Capture-MS Homo sapiens 14 GRIP2 80852 Affinity Capture-Western Homo sapiens 15 PPFIA3 8541 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 16 HIST1H2BK 85236 Cross-Linking-MS (XL-MS) Homo sapiens 17 DGUOK   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 PCLO 27445 Affinity Capture-Western Homo sapiens 19 ERC1 23085 Co-fractionation Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens 20 HECTD1 25831 Affinity Capture-MS Homo sapiens 21 OBSL1 23363 Affinity Capture-MS Homo sapiens 22 MYB   Reconstituted Complex Homo sapiens 23 PPFIA4   Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Two-hybrid Homo sapiens View the network

Pathways in which ERC2 is involved

No pathways found