Gene description for LSP1
Gene name lymphocyte-specific protein 1
Gene symbol LSP1
Other names/aliases WP34
pp52
Species Homo sapiens
 Database cross references - LSP1
ExoCarta ExoCarta_4046
Entrez Gene 4046
HGNC 6707
MIM 153432
UniProt P33241  
 LSP1 identified in exosomes derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
 Gene ontology annotations for LSP1
Molecular Function
    actin binding GO:0003779 TAS
    signal transducer activity GO:0004871 IEA
Biological Process
    movement of cell or subcellular component GO:0006928 TAS
    cellular defense response GO:0006968 TAS
    chemotaxis GO:0006935 IEA
    signal transduction GO:0007165 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    membrane GO:0016020 IDA
    actin cytoskeleton GO:0015629 TAS
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified LSP1 in exosomes
1
Experiment ID 79
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
CD81|MHCII
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W.
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
CD81|MHCII
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W.
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
 Protein-protein interactions for LSP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LSP1 is involved
No pathways found





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