Gene description for ESM1
Gene name endothelial cell-specific molecule 1
Gene symbol ESM1
Other names/aliases endocan
Species Homo sapiens
 Database cross references - ESM1
ExoCarta ExoCarta_11082
Entrez Gene 11082
HGNC 3466
MIM 601521
UniProt Q9NQ30  
 ESM1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for ESM1
Molecular Function
    hepatocyte growth factor receptor binding GO:0005171 IPI
    integrin binding GO:0005178 IPI
    insulin-like growth factor binding GO:0005520 IEA
Biological Process
    angiogenesis GO:0001525 IEP
    positive regulation of hepatocyte growth factor receptor signaling pathway GO:1902204 IDA
    sprouting angiogenesis GO:0002040 IMP
    regulation of cell growth GO:0001558 IEA
    positive regulation of cell proliferation GO:0008284 IDA
Subcellular Localization
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified ESM1 in exosomes
Experiment ID 126
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Antibody array
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for ESM1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ITGB2 3689
Invivo Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ESM1 is involved
No pathways found

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