Gene description for ORM1
Gene name orosomucoid 1
Gene symbol ORM1
Other names/aliases AGP-A
Species Homo sapiens
 Database cross references - ORM1
ExoCarta ExoCarta_5004
Entrez Gene 5004
HGNC 8498
MIM 138600
UniProt P02763  
 ORM1 identified in exosomes derived from the following tissue/cell type
Urine 25452312    
 Gene ontology annotations for ORM1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    transport GO:0006810 IEA
    regulation of immune system process GO:0002682 IEA
    acute-phase response GO:0006953 IEA
    negative regulation of interleukin-6 production GO:0032715 IDA
    negative regulation of tumor necrosis factor production GO:0032720 IDA
    inflammatory response GO:0006954 TAS
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    extracellular region GO:0005576 NAS
    blood microparticle GO:0072562 IDA
    extracellular space GO:0005615 IDA
 Experiment description of studies that identified ORM1 in exosomes
Experiment ID 238
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25452312    
Organism Homo sapiens
Experiment description N-linked (N-) glycoproteomics of urimary exosomes
Authors Saraswat M, Joenvaara S, Musante L, Peltoniemi H4, Holthofer H, Renkonen R.
Journal name Mol Cell Proteomics
Publication year 2014
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for ORM1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SERPINE1 5054
Invitro Homo sapiens
Two-hybrid Homo sapiens
2 ALB 213
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which ORM1 is involved
No pathways found

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