Gene description for VPS41
Gene name vacuolar protein sorting 41 homolog (S. cerevisiae)
Gene symbol VPS41
Other names/aliases HVPS41
HVSP41
hVps41p
Species Homo sapiens
 Database cross references - VPS41
ExoCarta ExoCarta_27072
Entrez Gene 27072
HGNC 12713
MIM 605485
UniProt P49754  
 VPS41 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for VPS41
Molecular Function
    microtubule binding GO:0008017 IEA
    protein binding GO:0005515 IPI
    GTPase binding GO:0051020 IBA
    zinc ion binding GO:0008270 IEA
    molecular_function GO:0003674 ND
Biological Process
    protein targeting to vacuole GO:0006623 IBA
    regulation of SNARE complex assembly GO:0035542 IBA
    vesicle-mediated transport GO:0016192 IEA
    vacuole fusion, non-autophagic GO:0042144 IBA
    biological_process GO:0008150 ND
    Golgi vesicle transport GO:0048193 IMP
Subcellular Localization
    late endosome GO:0005770 IBA
    lysosomal membrane GO:0005765 IDA
    CORVET complex GO:0033263 IBA
    early endosome GO:0005769 IEA
    cytosol GO:0005829 IDA
    membrane GO:0016020 IDA
    HOPS complex GO:0030897 IDA
    microtubule cytoskeleton GO:0015630 IEA
    Golgi-associated vesicle GO:0005798 IMP
 Experiment description of studies that identified VPS41 in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for VPS41
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which VPS41 is involved
No pathways found





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