Gene description for C2orf49
Gene name chromosome 2 open reading frame 49
Gene symbol C2orf49
Other names/aliases asw
Species Homo sapiens
 Database cross references - C2orf49
ExoCarta ExoCarta_79074
Entrez Gene 79074
HGNC 28772
UniProt Q9BVC5  
 C2orf49 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for C2orf49
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    biological_process GO:0008150 ND
    embryonic morphogenesis GO:0048598 IEA
Subcellular Localization
    tRNA-splicing ligase complex GO:0072669 IDA
 Experiment description of studies that identified C2orf49 in exosomes
1
Experiment ID 226
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD9|FLOT1
EV Membrane markers
LMNA|H2AFX|ATP5A1|TOMM20
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for C2orf49
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which C2orf49 is involved
No pathways found





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