Gene description for TAGLN3
Gene name transgelin 3
Gene symbol TAGLN3
Other names/aliases NP22
NP24
NP25
Species Homo sapiens
 Database cross references - TAGLN3
ExoCarta ExoCarta_29114
Vesiclepedia VP_29114
Entrez Gene 29114
HGNC 29868
MIM 607953
UniProt Q9UI15  
 TAGLN3 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for TAGLN3
Molecular Function
    protein binding GO:0005515 IPI
    actin filament binding GO:0051015 IBA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IEA
    actin filament organization GO:0007015 IBA
    central nervous system development GO:0007417 TAS
Subcellular Localization
    nucleus GO:0005634 IEA
    actin cytoskeleton GO:0015629 IBA
    synapse GO:0045202 IEA
 Experiment description of studies that identified TAGLN3 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for TAGLN3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ENO3 2027
Co-fractionation Homo sapiens
2 HSPE1 3336
Co-fractionation Homo sapiens
3 PGK2 5232
Co-fractionation Homo sapiens
4 GSTO1 9446
Co-fractionation Homo sapiens
5 SNX3 8724
Co-fractionation Homo sapiens
6 CLIC1 1192
Co-fractionation Homo sapiens
7 NME1-NME2 654364
Co-fractionation Homo sapiens
8 PIN1 5300
Co-fractionation Homo sapiens
9 TOLLIP 54472
Proximity Label-MS Homo sapiens
10 MTAP 4507
Co-fractionation Homo sapiens
11 HSD17B10 3028
Co-fractionation Homo sapiens
12 TKT 7086
Co-fractionation Homo sapiens
13 DUT 1854
Co-fractionation Homo sapiens
14 FKBP1A 2280
Co-fractionation Homo sapiens
15 PMM2 5373
Co-fractionation Homo sapiens
16 GDI2 2665
Co-fractionation Homo sapiens
17 TXN 7295
Co-fractionation Homo sapiens
18 PGK1 5230
Co-fractionation Homo sapiens
19 TAGLN2 8407
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
20 FABP5 2171
Co-fractionation Homo sapiens
21 NUTF2 10204
Co-fractionation Homo sapiens
22 YKT6 10652
Co-fractionation Homo sapiens
23 HSPA4 3308
Co-fractionation Homo sapiens
24 ENO2 2026
Co-fractionation Homo sapiens
25 SNX12 29934
Co-fractionation Homo sapiens
26 ENO1 2023
Co-fractionation Homo sapiens
27 HSPA4L 22824
Co-fractionation Homo sapiens
28 HSPH1 10808
Co-fractionation Homo sapiens
29 FKBP1B  
Co-fractionation Homo sapiens
30 HINT1 3094
Co-fractionation Homo sapiens
31 CLIC4 25932
Co-fractionation Homo sapiens
32 STIP1 10963
Co-fractionation Homo sapiens
33 SUMO3 6612
Co-fractionation Homo sapiens
34 UBXN1 51035
Co-fractionation Homo sapiens
35 UFM1 51569
Co-fractionation Homo sapiens
36 FABP7  
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which TAGLN3 is involved
No pathways found





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