Gene description for EOGT
Gene name EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
Gene symbol EOGT
Other names/aliases AER61
AOS4
C3orf64
EOGT1
Species Homo sapiens
 Database cross references - EOGT
ExoCarta ExoCarta_285203
Vesiclepedia VP_285203
Entrez Gene 285203
HGNC 28526
MIM 614789
UniProt Q5NDL2  
 EOGT identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for EOGT
Molecular Function
    protein binding GO:0005515 IPI
    protein O-acetylglucosaminyltransferase activity GO:0097363 IBA
    protein O-acetylglucosaminyltransferase activity GO:0097363 ISS
    RNA polymerase II C-terminal domain S5 O-GlcNAc transferase activity GO:0140842 IEA
    RNA polymerase II C-terminal domain S7 O-GlcNAc transferase activity GO:0140843 IEA
Biological Process
    protein O-linked glycosylation GO:0006493 ISS
    protein O-GlcNAcylation via threonine GO:0097370 IBA
Subcellular Localization
    endoplasmic reticulum lumen GO:0005788 IBA
 Experiment description of studies that identified EOGT in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for EOGT
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LY86  
Affinity Capture-MS Homo sapiens
2 APP 351
Reconstituted Complex Homo sapiens
3 CCL3  
Affinity Capture-MS Homo sapiens
4 PI15  
Affinity Capture-MS Homo sapiens
5 C7orf34  
Affinity Capture-MS Homo sapiens
6 GPIHBP1  
Affinity Capture-MS Homo sapiens
7 CCL3L1  
Affinity Capture-MS Homo sapiens
8 SCGB2A1 4246
Affinity Capture-MS Homo sapiens
9 LGI1  
Affinity Capture-MS Homo sapiens
10 FAM20C 56975
Affinity Capture-MS Homo sapiens
11 PRG3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 SCGB1D1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 OS9 10956
Affinity Capture-MS Homo sapiens
14 SLC13A4  
Two-hybrid Homo sapiens
15 RACGAP1 29127
Affinity Capture-MS Homo sapiens
16 FSTL4  
Affinity Capture-MS Homo sapiens
17 GGH 8836
Affinity Capture-MS Homo sapiens
18 NCR3  
Affinity Capture-MS Homo sapiens
19 IFI30  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 PLAUR 5329
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 PDGFRA 5156
Affinity Capture-MS Homo sapiens
22 PRG2  
Affinity Capture-MS Homo sapiens
23 ASS1 445
Co-fractionation Homo sapiens
24 RLN1  
Affinity Capture-MS Homo sapiens
25 DEFB136  
Affinity Capture-MS Homo sapiens
26 SFTPA2  
Affinity Capture-MS Homo sapiens
27 LYZL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 LY6G5C  
Affinity Capture-MS Homo sapiens
29 INSL5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 A2M 2
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 MFAP5  
Affinity Capture-MS Homo sapiens
32 LYZL6  
Affinity Capture-MS Homo sapiens
33 FAM209A 200232
Two-hybrid Homo sapiens
34 IDS  
Affinity Capture-MS Homo sapiens
35 GIP  
Affinity Capture-MS Homo sapiens
36 EYA4 2070
Affinity Capture-MS Homo sapiens
37 Mta2 23942
Affinity Capture-MS Mus musculus
38 Tpx2  
Affinity Capture-MS Mus musculus
39 CRISP2  
Affinity Capture-MS Homo sapiens
40 SCGB2A2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 C1orf54  
Affinity Capture-MS Homo sapiens
42 PSCA 8000
Affinity Capture-MS Homo sapiens
43 DEFB135  
Affinity Capture-MS Homo sapiens
44 SAMD9 54809
Affinity Capture-MS Homo sapiens
45 PTPRK 5796
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 LYPD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 TRAC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 F9 2158
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 BAGE2  
Affinity Capture-MS Homo sapiens
50 ST14 6768
Affinity Capture-MS Homo sapiens
51 CFC1  
Affinity Capture-MS Homo sapiens
52 SDF2L1 23753
Affinity Capture-MS Homo sapiens
53 CST9L  
Affinity Capture-MS Homo sapiens
54 PSG8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 TMPRSS13  
Affinity Capture-MS Homo sapiens
56 PLA2G10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which EOGT is involved
No pathways found





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