Gene description for RRP36
Gene name ribosomal RNA processing 36 homolog (S. cerevisiae)
Gene symbol RRP36
Other names/aliases C6orf153
dJ20C7.4
Species Homo sapiens
 Database cross references - RRP36
ExoCarta ExoCarta_88745
Vesiclepedia VP_88745
Entrez Gene 88745
HGNC 21374
MIM 613475
UniProt Q96EU6  
 RRP36 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for RRP36
Molecular Function
    RNA binding GO:0003723 HDA
Biological Process
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000462 IBA
    rRNA processing GO:0006364 IDA
    ribosomal small subunit biogenesis GO:0042274 IDA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    nucleolus GO:0005730 IBA
    nucleolus GO:0005730 IDA
    90S preribosome GO:0030686 IBA
 Experiment description of studies that identified RRP36 in exosomes
1
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for RRP36
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FDCSP  
Affinity Capture-MS Homo sapiens
2 SERF2 10169
Affinity Capture-MS Homo sapiens
3 TPX2  
Affinity Capture-MS Homo sapiens
4 SAA1 6288
Affinity Capture-MS Homo sapiens
5 TMEM14B  
Affinity Capture-MS Homo sapiens
6 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
7 MYCN  
Affinity Capture-MS Homo sapiens
8 UQCR11  
Affinity Capture-MS Homo sapiens
9 JPH3 57338
Affinity Capture-MS Homo sapiens
10 GAR1 54433
Affinity Capture-MS Homo sapiens
11 LSM12 124801
Affinity Capture-MS Homo sapiens
12 AIF1  
Affinity Capture-MS Homo sapiens
13 PSENEN  
Affinity Capture-MS Homo sapiens
14 CXCL6  
Affinity Capture-MS Homo sapiens
15 H2AFJ 55766
Affinity Capture-MS Homo sapiens
16 EHHADH 1962
Affinity Capture-MS Homo sapiens
17 ARF5 381
Affinity Capture-MS Homo sapiens
18 LMNB1 4001
Affinity Capture-MS Homo sapiens
19 C20orf197  
Affinity Capture-MS Homo sapiens
20 TAS2R42  
Affinity Capture-MS Homo sapiens
21 IFI6  
Affinity Capture-MS Homo sapiens
22 ANAPC15  
Affinity Capture-MS Homo sapiens
23 EZH1  
Affinity Capture-MS Homo sapiens
24 PEA15 8682
Affinity Capture-MS Homo sapiens
25 CENPA  
Affinity Capture-MS Homo sapiens
26 ANKRD50 57182
Affinity Capture-MS Homo sapiens
27 USP36  
Affinity Capture-MS Homo sapiens
28 IFI27L1  
Affinity Capture-MS Homo sapiens
29 KRTAP19-7  
Affinity Capture-MS Homo sapiens
30 RPS24 6229
Proximity Label-MS Homo sapiens
31 SPCS1 28972
Affinity Capture-MS Homo sapiens
32 MALL  
Affinity Capture-MS Homo sapiens
33 GAGE5  
Affinity Capture-MS Homo sapiens
34 RRP12 23223
Co-fractionation Homo sapiens
35 HNRNPAB 3182
Cross-Linking-MS (XL-MS) Homo sapiens
36 COL8A1 1295
Affinity Capture-MS Homo sapiens
37 KRAS 3845
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
38 ANOS1 3730
Affinity Capture-MS Homo sapiens
39 RHOB 388
Proximity Label-MS Homo sapiens
40 FBL 2091
Proximity Label-MS Homo sapiens
41 SRP19 6728
Affinity Capture-MS Homo sapiens
42 OBSL1 23363
Affinity Capture-MS Homo sapiens
43 TMSB4Y  
Affinity Capture-MS Homo sapiens
44 Set 56086
Affinity Capture-MS Mus musculus
45 ELOVL5 60481
Affinity Capture-MS Homo sapiens
46 CYCS 54205
Affinity Capture-MS Homo sapiens
47 DDX55  
Affinity Capture-MS Homo sapiens
48 KIF2C 11004
Affinity Capture-MS Homo sapiens
49 Nek9  
Affinity Capture-MS Mus musculus
50 SUMO1 7341
Affinity Capture-MS Homo sapiens
51 DNAJC22  
Affinity Capture-MS Homo sapiens
52 C1orf189  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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