Gene description for SAA1
Gene name	serum amyloid A1
Gene symbol	SAA1
Other names/aliases	PIG4 SAA SAA2 TP53I4
Species	Homo sapiens
Database cross references - SAA1
ExoCarta	ExoCarta_6288
Entrez Gene	6288
HGNC	10513
MIM	104750
UniProt	P0DJI8
SAA1 identified in exosomes derived from the following tissue/cell type
Prostate cancer cells	22723089
Saliva	19199708

Gene ontology annotations for SAA1

Molecular Function     heparin binding GO:0008201 IEA     G-protein coupled receptor binding GO:0001664 IDA     chemoattractant activity GO:0042056 IBA Biological Process     negative regulation of inflammatory response GO:0050728 NAS     positive regulation of cytosolic calcium ion concentration GO:0007204 NAS     receptor-mediated endocytosis GO:0006898 TAS     acute-phase response GO:0006953 NAS     innate immune response GO:0045087 TAS     lymphocyte chemotaxis GO:0048247 IDA     positive regulation of cytokine secretion GO:0050715 IDA     platelet activation GO:0030168 NAS     macrophage chemotaxis GO:0048246 IDA     positive chemotaxis GO:0050918 IBA     neutrophil chemotaxis GO:0030593 NAS     positive regulation of interleukin-1 secretion GO:0050716 NAS     positive regulation of cell adhesion GO:0045785 NAS     regulation of protein secretion GO:0050708 NAS     activation of MAPK activity GO:0000187 IDA Subcellular Localization     extracellular region GO:0005576 TAS     extracellular exosome GO:0070062 IDA     high-density lipoprotein particle GO:0034364 IEA     cytoplasmic microtubule GO:0005881 IDA     cytosol GO:0005829 NAS     endocytic vesicle lumen GO:0071682 TAS     extracellular space GO:0005615 IBA