Gene description for SAA2
Gene name serum amyloid A2
Gene symbol SAA2
Other names/aliases -
Species Homo sapiens
 Database cross references - SAA2
ExoCarta ExoCarta_6289
Entrez Gene 6289
HGNC 10514
MIM 104751
UniProt P0DJI9  
 SAA2 identified in exosomes derived from the following tissue/cell type
Prostate cancer cells 22723089    
Saliva 19199708    
 Gene ontology annotations for SAA2
Molecular Function
    chemoattractant activity GO:0042056 IBA
Biological Process
    positive chemotaxis GO:0050918 IBA
    acute-phase response GO:0006953 IEA
    cell chemotaxis GO:0060326 IBA
Subcellular Localization
    extracellular space GO:0005615 IBA
    high-density lipoprotein particle GO:0034364 IEA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified SAA2 in exosomes
1
Experiment ID 146
ISEV standards
EM
EV Biophysical techniques
HSP70|HSP90
EV Cytosolic markers
CD9
EV Membrane markers
HSP90B1
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors Hosseini-Beheshti E, Guns ES.
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name RWPE - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
2
Experiment ID 66
ISEV standards
IEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD63|CD81
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for SAA2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SAA2 is involved
No pathways found





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