Gene description for MAGI3
Gene name
membrane associated guanylate kinase, WW and PDZ domain containing 3
Gene symbol
MAGI3
Other names/aliases
MAGI-3 dJ730K3.2
Species
Homo sapiens
Database cross references - MAGI3
ExoCarta
ExoCarta_260425
Vesiclepedia
VP_260425
Entrez Gene
260425
HGNC
29647
MIM
615943
UniProt
Q5TCQ9
MAGI3 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells
26054723
Urine
19056867
Gene ontology annotations for MAGI3
Experiment description of studies that identified MAGI3 in exosomes
1
Experiment ID
235
MISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Enriched markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
2
Experiment ID
63
MISEV standards
✘
EV Biophysical techniques
✔
AQP2
EV Enriched markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19056867
Organism
Homo sapiens
Experiment description
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name
JASN
Publication year
2009
Sample
Urine
Sample name
Urine - Normal
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
Protein-protein interactions for MAGI3
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
PTPRB
5787
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
2
BAI1
Two-hybrid
Homo sapiens
3
PTEN
5728
Affinity Capture-Western
Homo sapiens
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
View the network
image/svg+xml
Pathways in which MAGI3 is involved
No pathways found