Gene description for C19orf26
Gene name chromosome 19 open reading frame 26
Gene symbol C19orf26
Other names/aliases DOS
Species Homo sapiens
 Database cross references - C19orf26
ExoCarta ExoCarta_255057
Vesiclepedia VP_255057
Entrez Gene 255057
HGNC 28617
UniProt Q8N350  
 C19orf26 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for C19orf26
Molecular Function
    protein binding GO:0005515 IPI
    transmembrane transporter binding GO:0044325 IBA
    transmembrane transporter binding GO:0044325 ISS
Biological Process
    negative regulation of calcium ion-dependent exocytosis GO:0045955 IBA
    negative regulation of calcium ion-dependent exocytosis GO:0045955 ISS
    negative regulation of voltage-gated calcium channel activity GO:1901386 ISS
    negative regulation of calcium ion transmembrane transport GO:1903170 ISS
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 ISS
    secretory granule GO:0030141 IBA
    secretory granule GO:0030141 ISS
    growth cone GO:0030426 ISS
    synaptic vesicle membrane GO:0030672 IEA
 Experiment description of studies that identified C19orf26 in exosomes
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for C19orf26
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 YWHAB 7529
Affinity Capture-MS Homo sapiens
2 YWHAH 7533
Affinity Capture-MS Homo sapiens
3 PHLPP1  
Proximity Label-MS Homo sapiens
4 GJD3  
Proximity Label-MS Homo sapiens
5 RAB35 11021
Proximity Label-MS Homo sapiens
6 FBXW11  
Affinity Capture-MS Homo sapiens
7 OCLN 100506658
Proximity Label-MS Homo sapiens
8 TMC6 11322
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 SHOC2 8036
Affinity Capture-MS Homo sapiens
10 FADS3 3995
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 YWHAZ 7534
Affinity Capture-MS Homo sapiens
12 GJA1 2697
Proximity Label-MS Homo sapiens
13 YWHAE 7531
Affinity Capture-MS Homo sapiens
14 TPTE  
Proximity Label-MS Homo sapiens
15 CACNB3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 CEP55 55165
Affinity Capture-MS Homo sapiens
17 STX4 6810
Proximity Label-MS Homo sapiens
18 CACNB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 STARD3 10948
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 LYN 4067
Proximity Label-MS Homo sapiens
21 MCAM 4162
Proximity Label-MS Homo sapiens
22 PPP1CC 5501
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 DNAJC5 80331
Proximity Label-MS Homo sapiens
24 UBASH3B 84959
Affinity Capture-MS Homo sapiens
25 DIRAS3  
Proximity Label-MS Homo sapiens
26 CD151 977
Affinity Capture-MS Homo sapiens
27 RAB9A 9367
Proximity Label-MS Homo sapiens
28 EPHA2 1969
Proximity Label-MS Homo sapiens
29 YWHAQ 10971
Affinity Capture-MS Homo sapiens
30 PPP1CA 5499
Affinity Capture-MS Homo sapiens
31 STX7 8417
Proximity Label-MS Homo sapiens
32 KRAS 3845
Proximity Label-MS Homo sapiens
33 RHOB 388
Proximity Label-MS Homo sapiens
34 YWHAG 7532
Affinity Capture-MS Homo sapiens
35 C11orf52 91894
Proximity Label-MS Homo sapiens
36 CAV1 857
Proximity Label-MS Homo sapiens
37 BIN1 274
Affinity Capture-MS Homo sapiens
38 FLOT1 10211
Proximity Label-MS Homo sapiens
39 SCCPDH 51097
Affinity Capture-MS Homo sapiens
40 STX6 10228
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which C19orf26 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here