Gene description for SHROOM1
Gene name shroom family member 1
Gene symbol SHROOM1
Other names/aliases APXL2
Species Homo sapiens
 Database cross references - SHROOM1
ExoCarta ExoCarta_134549
Vesiclepedia VP_134549
Entrez Gene 134549
HGNC 24084
MIM 611179
UniProt Q2M3G4  
 SHROOM1 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for SHROOM1
Molecular Function
    myosin II binding GO:0045159 ISS
    actin filament binding GO:0051015 IBA
    actin filament binding GO:0051015 ISS
Biological Process
    cell morphogenesis GO:0000902 IBA
    cell morphogenesis GO:0000902 ISS
    actin filament bundle assembly GO:0051017 IBA
    actin filament bundle assembly GO:0051017 ISS
Subcellular Localization
    microtubule GO:0005874 IEA
    adherens junction GO:0005912 IBA
    apical plasma membrane GO:0016324 IBA
    cortical actin cytoskeleton GO:0030864 IBA
    apical junction complex GO:0043296 IBA
 Experiment description of studies that identified SHROOM1 in exosomes
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SHROOM1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 YWHAH 7533
Affinity Capture-MS Homo sapiens
2 NYX  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 MCAM 4162
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
4 YWHAQ 10971
Affinity Capture-MS Homo sapiens
5 YWHAG 7532
Affinity Capture-MS Homo sapiens
6 BAG2 9532
Affinity Capture-MS Homo sapiens
7 MLLT4 4301
Proximity Label-MS Homo sapiens
8 DYRK1A 1859
Affinity Capture-MS Homo sapiens
9 DUSP16  
Affinity Capture-MS Homo sapiens
10 XPO1 7514
Affinity Capture-MS Homo sapiens
11 YWHAB 7529
Affinity Capture-MS Homo sapiens
12 HSPA2 3306
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SHROOM1 is involved
No pathways found





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