Gene description for PCDH10
Gene name protocadherin 10
Gene symbol PCDH10
Other names/aliases OL-PCDH
PCDH19
Species Homo sapiens
 Database cross references - PCDH10
ExoCarta ExoCarta_57575
Vesiclepedia VP_57575
Entrez Gene 57575
HGNC 13404
MIM 608286
UniProt Q9P2E7  
 PCDH10 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for PCDH10
Molecular Function
    calcium ion binding GO:0005509 IEA
Biological Process
    cell adhesion GO:0007155 IBA
    homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 IEA
    nervous system development GO:0007399 IEA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    postsynaptic membrane GO:0045211 IEA
    glutamatergic synapse GO:0098978 IEA
 Experiment description of studies that identified PCDH10 in exosomes
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for PCDH10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PTGIR  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 RYK 6259
Affinity Capture-MS Homo sapiens
3 BET1 10282
Affinity Capture-MS Homo sapiens
4 FBXO45 200933
Affinity Capture-MS Homo sapiens
5 PPP1R15B  
Affinity Capture-MS Homo sapiens
6 DDHD2 23259
Affinity Capture-MS Homo sapiens
7 PKN3 29941
Affinity Capture-MS Homo sapiens
8 MYADM 91663
Affinity Capture-MS Homo sapiens
9 PCDHGB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 UPK2 7379
Affinity Capture-MS Homo sapiens
11 OCLN 100506658
Affinity Capture-MS Homo sapiens
12 RNFT1  
Affinity Capture-MS Homo sapiens
13 RAD23A 5886
Affinity Capture-Western Homo sapiens
14 FNDC3B 64778
Affinity Capture-MS Homo sapiens
15 ATP1A3 478
Affinity Capture-MS Homo sapiens
16 TMEM63B 55362
Affinity Capture-MS Homo sapiens
17 NRSN1  
Affinity Capture-MS Homo sapiens
18 FCGRT 2217
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 SMIM5  
Affinity Capture-MS Homo sapiens
20 TMEM223  
Affinity Capture-MS Homo sapiens
21 PCDHGB4 8641
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 RP2 6102
Affinity Capture-MS Homo sapiens
23 PCDH12 51294
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 TMEM30B 161291
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 SPSB4  
Affinity Capture-MS Homo sapiens
26 LMAN2L 81562
Affinity Capture-MS Homo sapiens
27 TRIM26 7726
Affinity Capture-MS Homo sapiens
28 SLC34A2 10568
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 BTRC 8945
Affinity Capture-MS Homo sapiens
30 CACNA1H  
Affinity Capture-MS Homo sapiens
31 DLG4  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
32 SIRT5 23408
Affinity Capture-MS Homo sapiens
33 DCAKD 79877
Affinity Capture-MS Homo sapiens
34 IL3RA  
Affinity Capture-MS Homo sapiens
35 IFITM1 8519
Affinity Capture-MS Homo sapiens
36 RHBDD1 84236
Affinity Capture-MS Homo sapiens
37 FBXW11  
Affinity Capture-MS Homo sapiens
38 PCDHGB2  
Affinity Capture-MS Homo sapiens
39 NDC1 55706
Affinity Capture-MS Homo sapiens
40 SLC27A3 11000
Affinity Capture-MS Homo sapiens
41 RPL23 9349
Affinity Capture-MS Homo sapiens
42 TMEM130  
Affinity Capture-MS Homo sapiens
43 SLC30A7 148867
Affinity Capture-MS Homo sapiens
44 ARL17A  
Affinity Capture-MS Homo sapiens
45 FNDC3A 22862
Affinity Capture-MS Homo sapiens
46 CISD2 493856
Affinity Capture-MS Homo sapiens
47 SRC 6714
Affinity Capture-MS Homo sapiens
48 HECTD1 25831
Affinity Capture-MS Homo sapiens
49 ATP6V0A2 23545
Affinity Capture-MS Homo sapiens
50 PSMC2 5701
Affinity Capture-Western Homo sapiens
51 MAGI1  
Affinity Capture-MS Homo sapiens
52 TRAF3 7187
Affinity Capture-MS Homo sapiens
53 ERMP1 79956
Affinity Capture-MS Homo sapiens
54 MYCBP2 23077
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PCDH10 is involved
No pathways found





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