Gene description for RTN4R
Gene name	reticulon 4 receptor
Gene symbol	RTN4R
Other names/aliases	NGR NOGOR
Species	Homo sapiens
Database cross references - RTN4R
ExoCarta	ExoCarta_65078
Vesiclepedia	VP_65078
Entrez Gene	65078
HGNC	18601
MIM	605566
UniProt	Q9BZR6
RTN4R identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for RTN4R

Molecular Function     protein binding GO:0005515 IPI     heparin binding GO:0008201 ISS     chondroitin sulfate binding GO:0035374 ISS     signaling receptor activity GO:0038023 ISS     signaling receptor activity GO:0038023 NAS     neuregulin receptor activity GO:0038131 ISS     protein-containing complex binding GO:0044877 IEA     ganglioside GM1 binding GO:1905573 IBA     ganglioside GM1 binding GO:1905573 IDA     ganglioside GT1b binding GO:1905576 IBA     ganglioside GT1b binding GO:1905576 IDA Biological Process     cell surface receptor signaling pathway GO:0007166 ISS     axonogenesis GO:0007409 IEA     negative regulation of neuron projection development GO:0010977 ISS     corpus callosum development GO:0022038 ISS     neuronal signal transduction GO:0023041 ISS     negative regulation of axon extension GO:0030517 ISS     positive regulation of Rho protein signal transduction GO:0035025 IBA     positive regulation of Rho protein signal transduction GO:0035025 IMP     positive regulation of GTPase activity GO:0043547 ISS     negative regulation of axon regeneration GO:0048681 ISS     regulation of postsynapse assembly GO:0150052 IEA Subcellular Localization     endoplasmic reticulum GO:0005783 IDA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 ISS     plasma membrane GO:0005886 TAS     external side of plasma membrane GO:0009897 IBA     external side of plasma membrane GO:0009897 IMP     cell surface GO:0009986 IDA     neuron projection GO:0043005 ISS     neuronal cell body GO:0043025 ISS     dendritic shaft GO:0043198 ISS     perikaryon GO:0043204 IEA     axonal growth cone GO:0044295 ISS     membrane raft GO:0045121 ISS     extracellular exosome GO:0070062 HDA     presynapse GO:0098793 IEA     glutamatergic synapse GO:0098978 IEA