Gene description for Ptcd2
Gene name pentatricopeptide repeat domain 2
Gene symbol Ptcd2
Other names/aliases 1190005P08Rik
Species Mus musculus
 Database cross references - Ptcd2
ExoCarta ExoCarta_68927
Vesiclepedia VP_68927
Entrez Gene 68927
UniProt Q8R3K3  
 Ptcd2 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ptcd2
Biological Process
    kidney development GO:0001822 IMP
    liver development GO:0001889 IMP
    mRNA processing GO:0006397 IEA
    mitochondrion organization GO:0007005 IBA
    mitochondrion organization GO:0007005 IMP
    heart development GO:0007507 IMP
    regulation of gene expression GO:0010468 IMP
    regulation of mRNA processing GO:0050684 IBA
    regulation of mRNA processing GO:0050684 IMP
    muscle cell development GO:0055001 IMP
    ventricular cardiac muscle tissue morphogenesis GO:0055010 IMP
Subcellular Localization
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 ISO
 Experiment description of studies that identified Ptcd2 in sEVs
1
Experiment ID 15
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ptcd2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 KRT31 3881
Two-hybrid Homo sapiens
2 CPSF7 79869
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which Ptcd2 is involved
No pathways found





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