Gene description for CRYGS
Gene name crystallin, gamma S
Gene symbol CRYGS
Other names/aliases CRYG8
CTRCT20
Species Homo sapiens
 Database cross references - CRYGS
ExoCarta ExoCarta_1427
Entrez Gene 1427
HGNC 2417
MIM 123730
UniProt P22914  
 CRYGS identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for CRYGS
Molecular Function
    structural constituent of eye lens GO:0005212 IEA
Biological Process
    morphogenesis of an epithelium GO:0002009 IEA
    lens development in camera-type eye GO:0002088 IEA
 Experiment description of studies that identified CRYGS in exosomes
1
Experiment ID 234
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for CRYGS
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CRYGS is involved
No pathways found





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