Gene description for Asna1
Gene name arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Gene symbol Asna1
Other names/aliases 1810048H22Rik
ArsA
Species Mus musculus
 Database cross references - Asna1
ExoCarta ExoCarta_56495
Vesiclepedia VP_56495
Entrez Gene 56495
UniProt O54984  
 Asna1 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
Pancreatic cells 19351151    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Asna1
Molecular Function
    ATP binding GO:0005524 IEA
    metal ion binding GO:0046872 IEA
    hydrolase activity GO:0016787 IEA
    ATPase activity GO:0016887 IEA
    nucleotide binding GO:0000166 IEA
Biological Process
    transport GO:0006810 IEA
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 IEA
    nucleolus GO:0005730 ISO
    endoplasmic reticulum GO:0005783 IEA
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Asna1 in exosomes
1
Experiment ID 907
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 188
MISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Enriched markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 908
MISEV standards
EM
EV Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
HSPA5
EV Negative markers
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Asna1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 BMPR2 659
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which Asna1 is involved
PathwayEvidenceSource
XBP1(S) activates chaperone genes IEA Reactome





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