Experiment description of studies that identified Serpina3k in exosomes

1 Experiment ID 303 MISEV standards ✔ EM EV Biophysical techniques ✔ Cd63|Cd81|Cd9 EV Enriched markers ✘ EV Negative markers ✔ NTA EV Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 33431899     Organism Mus musculus Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Authors Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG. Journal name Nat Commun Publication year 2021 Sample Faeces Sample name Intestinal epithelial cells - C57BL/6 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation Flotation density - Molecules identified in the study Protein Lipid miRNA Methods used in the study Western blotting Mass spectrometry Immunofluorescence miRNA array HPLC

2 Experiment ID 304 MISEV standards ✔ EM EV Biophysical techniques ✔ Cd63|Cd81|Cd9 EV Enriched markers ✘ EV Negative markers ✔ NTA EV Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 33431899     Organism Mus musculus Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Authors Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG. Journal name Nat Commun Publication year 2021 Sample Faeces Sample name Intestinal epithelial cells - C57BL/6 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation Flotation density - Molecules identified in the study Protein Lipid miRNA Methods used in the study Western blotting Mass spectrometry Immunofluorescence miRNA array HPLC

Protein-protein interactions for Serpina3k

Protein Interactor ExoCarta ID Identification method PubMed Species 1 BMPR2 659 Affinity Capture-MS Homo sapiens View the network

Pathways in which Serpina3k is involved

No pathways found