Gene description for KLK1
Gene name kallikrein 1
Gene symbol KLK1
Other names/aliases KLKR
Species Homo sapiens
 Database cross references - KLK1
ExoCarta ExoCarta_3816
Entrez Gene 3816
HGNC 6357
MIM 147910
UniProt P06870  
 KLK1 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for KLK1
Molecular Function
    serine-type endopeptidase activity GO:0004252 NAS
Biological Process
    proteolysis GO:0006508 IEA
Subcellular Localization
    nucleus GO:0005634 IDA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified KLK1 in exosomes
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for KLK1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SERPINA4 5267
Invitro Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
2 SERPINA5 5104
Affinity Capture-MS Homo sapiens
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