Gene description for CD68
Gene name CD68 molecule
Gene symbol CD68
Other names/aliases GP110
LAMP4
SCARD1
Species Homo sapiens
 Database cross references - CD68
ExoCarta ExoCarta_968
Entrez Gene 968
HGNC 1693
MIM 153634
UniProt P34810  
 CD68 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells 20124223    
 Gene ontology annotations for CD68
Biological Process
    cellular response to organic substance GO:0071310 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    endosome membrane GO:0010008 IEA
    lysosomal membrane GO:0005765 IEA
    plasma membrane GO:0005886 IEA
    membrane GO:0016020 TAS
 Experiment description of studies that identified CD68 in exosomes
1
Experiment ID 191
ISEV standards
EV Biophysical techniques
Alix
EV Cytosolic markers
CD81|CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CD68
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CD68 is involved
No pathways found





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