Gene description for TTC28
Gene name tetratricopeptide repeat domain 28
Gene symbol TTC28
Other names/aliases TPRBK
Species Homo sapiens
 Database cross references - TTC28
ExoCarta ExoCarta_23331
Entrez Gene 23331
HGNC 29179
MIM 615098
UniProt Q96AY4  
 TTC28 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for TTC28
Biological Process
    regulation of mitotic cell cycle GO:0007346 IEA
    mitotic nuclear division GO:0007067 IEA
    cell division GO:0051301 IEA
Subcellular Localization
    spindle pole GO:0000922 IEA
    cytoplasm GO:0005737 IEA
    centrosome GO:0005813 IEA
    midbody GO:0030496 IEA
 Experiment description of studies that identified TTC28 in exosomes
1
Experiment ID 226
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD9|FLOT1
EV Membrane markers
LMNA|H2AFX|ATP5A1|TOMM20
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for TTC28
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TTC28 is involved
No pathways found





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