Gene description for DNAH7
Gene name dynein, axonemal, heavy chain 7
Gene symbol DNAH7
Other names/aliases -
Species Homo sapiens
 Database cross references - DNAH7
ExoCarta ExoCarta_56171
Entrez Gene 56171
HGNC 18661
MIM 610061
UniProt Q8WXX0  
 DNAH7 identified in exosomes derived from the following tissue/cell type
Plasma 19028452    
Thymus 23844026    
 Gene ontology annotations for DNAH7
Molecular Function
    ATPase activity GO:0016887 IEA
    calcium ion binding GO:0005509 IEA
    microtubule motor activity GO:0003777 NAS
    ATP binding GO:0005524 IEA
Biological Process
    metabolic process GO:0008152 NAS
    cilium or flagellum-dependent cell motility GO:0001539 NAS
    inner dynein arm assembly GO:0036159 IMP
    cilium movement GO:0003341 IMP
Subcellular Localization
    cilium GO:0005929 IDA
    inner dynein arm GO:0036156 IMP
    axonemal dynein complex GO:0005858 NAS
    microtubule GO:0005874 IEA
 Experiment description of studies that identified DNAH7 in exosomes
1
Experiment ID 44
ISEV standards
IEM
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19028452    
Organism Homo sapiens
Experiment description Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein.
Authors Looze C, Yui D, Leung L, Ingham M, Kaler M, Yao X, Wu WW, Shen RF, Daniels MP, Levine SJ
Journal name BBRC
Publication year 2009
Sample Plasma
Sample name Plasma
Isolation/purification methods Filtration
Size exclusion
Sucrose density gradient
Flotation density 1.15-1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
2
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DNAH7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which DNAH7 is involved
No pathways found





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