Gene description for CCDC125
Gene name coiled-coil domain containing 125
Gene symbol CCDC125
Other names/aliases KENAE
Species Homo sapiens
 Database cross references - CCDC125
ExoCarta ExoCarta_202243
Entrez Gene 202243
HGNC 28924
MIM 613781
UniProt Q86Z20  
 CCDC125 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for CCDC125
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified CCDC125 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for CCDC125
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CCDC125 is involved
No pathways found





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