Gene description for SMYD5
Gene name SMYD family member 5
Gene symbol SMYD5
Other names/aliases NN8-4AG
RAI15
RRG1
ZMYND23
Species Homo sapiens
 Database cross references - SMYD5
ExoCarta ExoCarta_10322
Entrez Gene 10322
HGNC 16258
UniProt Q6GMV2  
 SMYD5 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for SMYD5
Molecular Function
    molecular_function GO:0003674 ND
    metal ion binding GO:0046872 IEA
    methyltransferase activity GO:0008168 IEA
Biological Process
    methylation GO:0032259 IEA
    biological_process GO:0008150 ND
Subcellular Localization
    cellular_component GO:0005575 ND
 Experiment description of studies that identified SMYD5 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for SMYD5
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SMYD5 is involved
No pathways found





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