Gene description for PELI1
Gene name	pellino E3 ubiquitin protein ligase 1
Gene symbol	PELI1
Other names/aliases	-
Species	Homo sapiens
Database cross references - PELI1
ExoCarta	ExoCarta_57162
Vesiclepedia	VP_57162
Entrez Gene	57162
HGNC	8827
MIM	614797
UniProt	Q96FA3
PELI1 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for PELI1

Molecular Function     ligase activity GO:0016874 IEA     ubiquitin-protein transferase activity GO:0004842 IEA     protein binding GO:0005515 IPI Biological Process     response to lipopolysaccharide GO:0032496 IEA     negative regulation of T cell proliferation GO:0042130 IEA     toll-like receptor signaling pathway GO:0002224 TAS     positive regulation of B cell proliferation GO:0030890 IEA     innate immune response GO:0045087 TAS     positive regulation of protein ubiquitination GO:0031398 IEA     positive regulation of toll-like receptor 3 signaling pathway GO:0034141 IEA     toll-like receptor 9 signaling pathway GO:0034162 TAS     negative regulation of NF-kappaB transcription factor activity GO:0032088 IEA     toll-like receptor 5 signaling pathway GO:0034146 TAS     toll-like receptor TLR6:TLR2 signaling pathway GO:0038124 TAS     Toll signaling pathway GO:0008063 IEA     protein K48-linked ubiquitination GO:0070936 IEA     response to dsRNA GO:0043331 IEA     positive regulation of cytokine production GO:0001819 IEA     positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 TAS     toll-like receptor 4 signaling pathway GO:0034142 TAS     positive regulation of toll-like receptor 4 signaling pathway GO:0034145 IEA     toll-like receptor 2 signaling pathway GO:0034134 TAS     toll-like receptor TLR1:TLR2 signaling pathway GO:0038123 TAS     MyD88-dependent toll-like receptor signaling pathway GO:0002755 TAS     toll-like receptor 10 signaling pathway GO:0034166 TAS Subcellular Localization     nucleus GO:0005634 IEA     cytosol GO:0005829 TAS