Gene description for PELI1
Gene name	pellino E3 ubiquitin protein ligase 1
Gene symbol	PELI1
Other names/aliases	-
Species	Homo sapiens
Database cross references - PELI1
ExoCarta	ExoCarta_57162
Vesiclepedia	VP_57162
Entrez Gene	57162
HGNC	8827
MIM	614797
UniProt	Q96FA3
PELI1 identified in sEVs derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for PELI1

Molecular Function     protein binding GO:0005515 IPI     ubiquitin-ubiquitin ligase activity GO:0034450 IDA     ubiquitin-ubiquitin ligase activity GO:0034450 TAS     ubiquitin protein ligase activity GO:0061630 EXP     ubiquitin protein ligase activity GO:0061630 IBA     ubiquitin protein ligase activity GO:0061630 IDA Biological Process     positive regulation of cytokine production GO:0001819 IEA     DNA repair GO:0006281 IEA     regulation of Toll signaling pathway GO:0008592 IEA     positive regulation of B cell proliferation GO:0030890 IEA     positive regulation of protein ubiquitination GO:0031398 IEA     response to lipopolysaccharide GO:0032496 IDA     positive regulation of toll-like receptor 3 signaling pathway GO:0034141 IEA     positive regulation of toll-like receptor 4 signaling pathway GO:0034145 IEA     T cell proliferation GO:0042098 IEA     negative regulation of T cell proliferation GO:0042130 IEA     positive regulation of canonical NF-kappaB signal transduction GO:0043123 TAS     proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IMP     response to dsRNA GO:0043331 IEA     regulation of necroptotic process GO:0060544 TAS     negative regulation of necroptotic process GO:0060546 IMP     protein K63-linked ubiquitination GO:0070534 IDA     protein K63-linked ubiquitination GO:0070534 IMP     protein K48-linked ubiquitination GO:0070936 IBA     protein K48-linked ubiquitination GO:0070936 IMP     negative regulation of TORC1 signaling GO:1904262 IDA     positive regulation of double-strand break repair via homologous recombination GO:1905168 IDA Subcellular Localization     nucleus GO:0005634 IEA     cytoplasm GO:0005737 IC     cytosol GO:0005829 TAS     site of double-strand break GO:0035861 IDA