Gene description for TXNDC17
Gene name
thioredoxin domain containing 17
Gene symbol
TXNDC17
Other names/aliases
TRP14 TXNL5
Species
Homo sapiens
Database cross references - TXNDC17
ExoCarta
ExoCarta_84817
Entrez Gene
84817
HGNC
28218
UniProt
Q9BRA2
TXNDC17 identified in exosomes derived from the following tissue/cell type
Squamous carcinoma cells
20124223
Urine
19056867
Gene ontology annotations for TXNDC17
Experiment description of studies that identified TXNDC17 in exosomes
1
Experiment ID
191
ISEV standards
✘
EV Biophysical techniques
✔
Alix
EV Cytosolic markers
✔
CD81|CD9
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20124223
Organism
Homo sapiens
Experiment description
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors
Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name
Mol Cell Proteomics
Publication year
2010
Sample
Squamous carcinoma cells
Sample name
Squamous carcinoma cell (A431)
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
2
Experiment ID
63
ISEV standards
✘
EV Biophysical techniques
✘
EV Cytosolic markers
✔
AQP2
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19056867
Organism
Homo sapiens
Experiment description
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name
JASN
Publication year
2009
Sample
Urine
Sample name
Urine - Normal
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
Protein-protein interactions for TXNDC17
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
DYNLL1
8655
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
2
INS
3630
Affinity Capture-MS
Homo sapiens
Biochemical Activity
Homo sapiens
3
CFL1
1072
Affinity Capture-MS
Homo sapiens
4
AVP
Biochemical Activity
Homo sapiens
5
OXT
Biochemical Activity
Homo sapiens
View the network
image/svg+xml
Pathways in which TXNDC17 is involved
No pathways found