Gene description for CLIC2
Gene name	chloride intracellular channel 2
Gene symbol	CLIC2
Other names/aliases	CLIC2b MRXS32 XAP121
Species	Homo sapiens
Database cross references - CLIC2
ExoCarta	ExoCarta_1193
Entrez Gene	1193
HGNC	2063
MIM	300138
UniProt	O15247
CLIC2 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for CLIC2

Molecular Function     glutathione peroxidase activity GO:0004602 IDA     chloride channel activity GO:0005254 IEA     protein binding GO:0005515 IPI     voltage-gated ion channel activity GO:0005244 IEA     glutathione transferase activity GO:0004364 IDA Biological Process     regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 IDA     positive regulation of binding GO:0051099 IDA     negative regulation of ryanodine-sensitive calcium-release channel activity GO:0060315 IDA     signal transduction GO:0007165 TAS     transport GO:0006810 TAS     chloride transmembrane transport GO:1902476 IEA     oxidation-reduction process GO:0055114 IDA     regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 IC Subcellular Localization     intracellular GO:0005622 IDA     nucleus GO:0005634 TAS     cytoplasm GO:0005737 TAS     chloride channel complex GO:0034707 IEA