Gene description for SLC35E2
Gene name solute carrier family 35, member E2
Gene symbol SLC35E2
Other names/aliases -
Species Homo sapiens
 Database cross references - SLC35E2
ExoCarta ExoCarta_9906
Vesiclepedia VP_9906
Entrez Gene 9906
HGNC 20863
UniProt P0CK97  
 SLC35E2 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for SLC35E2
Molecular Function
    protein binding GO:0005515 IPI
    antiporter activity GO:0015297 IBA
Biological Process
    transmembrane transport GO:0055085 IBA
Subcellular Localization
    Golgi apparatus GO:0005794 IBA
    membrane GO:0016020 IEA
 Experiment description of studies that identified SLC35E2 in exosomes
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for SLC35E2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ADAM33 80332
Two-hybrid Homo sapiens
2 PLP1 5354
Two-hybrid Homo sapiens
3 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
4 TMEM132D  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which SLC35E2 is involved
No pathways found





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