Gene description for Zc3h11a
Gene name zinc finger CCCH type containing 11A
Gene symbol Zc3h11a
Other names/aliases 1110003F06Rik
5730454B08Rik
G630041M05Rik
Zc3hdc11a
Zc3hh11a
mKIAA0663
Species Mus musculus
 Database cross references - Zc3h11a
ExoCarta ExoCarta_70579
Vesiclepedia VP_70579
Entrez Gene 70579
UniProt Q6NZF1  
 Zc3h11a identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Zc3h11a
Molecular Function
    metal ion binding GO:0046872 IEA
Biological Process
    poly(A)+ mRNA export from nucleus GO:0016973 IBA
    poly(A)+ mRNA export from nucleus GO:0016973 ISS
Subcellular Localization
    transcription export complex GO:0000346 ISO
    transcription export complex GO:0000346 ISS
 Experiment description of studies that identified Zc3h11a in exosomes
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Zc3h11a
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Nphp4  
Affinity Capture-MS Mus musculus
2 EXOSC7 23016
Two-hybrid Homo sapiens
3 Eed  
Affinity Capture-MS Mus musculus
4 Ube2i  
Two-hybrid Mus musculus
5 CTTN 2017
Two-hybrid Homo sapiens
6 Atg16l1  
Affinity Capture-MS Mus musculus
7 Celf1  
Two-hybrid Mus musculus
View the network image/svg+xml



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